The prognostic value of biological markers in paediatric Hodgkin lymphoma Piero Farruggia, Giuseppe Puccio, Alessandra Sala, Alessandra Todesco, Salvatore.

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Transcript della presentazione:

The prognostic value of biological markers in paediatric Hodgkin lymphoma Piero Farruggia, Giuseppe Puccio, Alessandra Sala, Alessandra Todesco, Salvatore Buffardi, Alberto Garaventa, Gaetano Bottigliero, Maurizio Bianchi, Marco Zecca, Franco Locatelli, Andrea Pession, Marta Pillon, Claudio Favre, Salvatore D'Amico, Massimo Provenzi, Angela Trizzino, Giulio Andrea Zanazzo, Antonella Sau, Nicola Santoro, Giulio Murgia, Tommaso Casini, Maurizio Mascarin, Roberta Burnelli Simone Cesaro, Ada Zaccaron, Patrizia Bertolini, Caterina Consarino, Grazia Iaria, Roberta Pericoli, Paolo Pierani, Fausto Fedeli, Monica Cellini, Raffaela De Santis, Fulvio Porta, Mauro Caini, Carlo Cosmi, Nadia Mirra, Adele Civino, Domenico Sperlì, Luigi Nespoli, Maurizio Caniglia, Katia Perruccio, Paolo D'Angelo, Eva Passone, Roberta Caruso, Giovanni Scarzello, Roberto Rondelli Piero Farruggia, Giuseppe Puccio, Alessandra Sala, Alessandra Todesco, Salvatore Buffardi, Alberto Garaventa, Gaetano Bottigliero, Maurizio Bianchi, Marco Zecca, Franco Locatelli, Andrea Pession, Marta Pillon, Claudio Favre, Salvatore D'Amico, Massimo Provenzi, Angela Trizzino, Giulio Andrea Zanazzo, Antonella Sau, Nicola Santoro, Giulio Murgia, Tommaso Casini, Maurizio Mascarin, Roberta Burnelli Simone Cesaro, Ada Zaccaron, Patrizia Bertolini, Caterina Consarino, Grazia Iaria, Roberta Pericoli, Paolo Pierani, Fausto Fedeli, Monica Cellini, Raffaela De Santis, Fulvio Porta, Mauro Caini, Carlo Cosmi, Nadia Mirra, Adele Civino, Domenico Sperlì, Luigi Nespoli, Maurizio Caniglia, Katia Perruccio, Paolo D'Angelo, Eva Passone, Roberta Caruso, Giovanni Scarzello, Roberto Rondelli European Journal of Cancer Volume 52, Pages 33-40 (January 2016) DOI: 10.1016/j.ejca.2015.09.003 Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. 1 The curve shows the “true positive rate”/“false positive rate” tradeoff at each tested cutoff. Cutoff scale can be read on the colourized scale. Area under curve is a cutoff independent measure which is equal to the value of the Wilcoxon–Mann–Whitney test statistic and corresponds to the probability that the classifier will score a randomly drawn positive sample higher than randomly drawn negative sample. European Journal of Cancer 2016 52, 33-40DOI: (10.1016/j.ejca.2015.09.003) Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. 2 Kaplan–Meier survival curve for ferritin categorised at the 209 cutoff. European Journal of Cancer 2016 52, 33-40DOI: (10.1016/j.ejca.2015.09.003) Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. 3 Kaplan–Meier curve based on the number of risk factors. European Journal of Cancer 2016 52, 33-40DOI: (10.1016/j.ejca.2015.09.003) Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. A.1 Chi square statistic for ferritin ROC curve. European Journal of Cancer 2016 52, 33-40DOI: (10.1016/j.ejca.2015.09.003) Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. A.2 Survival curve. European Journal of Cancer 2016 52, 33-40DOI: (10.1016/j.ejca.2015.09.003) Copyright © 2015 Elsevier Ltd Terms and Conditions