Cetuximab plus irinotecan after irinotecan failure in elderly metastatic colorectal cancer patients: Clinical outcome according to KRAS and BRAF mutational.

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Cetuximab plus irinotecan after irinotecan failure in elderly metastatic colorectal cancer patients: Clinical outcome according to KRAS and BRAF mutational status  Lorenzo Fornaro, Giacomo Giulio Baldi, Gianluca Masi, Giacomo Allegrini, Fotios Loupakis, Enrico Vasile, Samanta Cupini, Irene Stasi, Lisa Salvatore, Chiara Cremolini, Bruno Vincenzi, Daniele Santini, Giuseppe Tonini, Francesco Graziano, Annamaria Ruzzo, Emanuele Canestrari, Mauro Magnani, Alfredo Falcone  Critical Reviews in Oncology / Hematology  Volume 78, Issue 3, Pages 243-251 (June 2011) DOI: 10.1016/j.critrevonc.2010.06.003 Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 PFS and OS curves. (A) PFS in all patients. (B) OS in all patients. (C) PFS according to KRAS mutational status. (D) OS according to KRAS mutational status. (E) PFS according to BRAF mutational status. (F) OS according to BRAF mutational status. (G) PFS according to KRAS and BRAF mutational status. (H) OS according to KRAS and BRAF mutational status. n, number; pts, patients; wt, wild-type; mut, mutated. Critical Reviews in Oncology / Hematology 2011 78, 243-251DOI: (10.1016/j.critrevonc.2010.06.003) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions