Volume 68, Issue 1, Pages (January 2018)

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Transcript della presentazione:

Volume 68, Issue 1, Pages 33-41 (January 2018) Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV Aimilia Karampatou, Xue Han, Loreta A. Kondili, Gloria Taliani, Alessia Ciancio, Filomena Morisco, Rosina Maria Critelli, Enrica Baraldi, Veronica Bernabucci, Giulia Troshina, Maria Guarino, Simonetta Tagliavini, Federica D'Ambrosio, Laura Bristot, Laura Turco, Stefano Rosato, Stefano Vella, Tommaso Trenti, Isabella Neri, Antonio La Marca, Shivaji Manthena, Andrea S. Goldstein, Savino Bruno, Yanjun Bao, Yuri Sanchez Gonzalez, Erica Villa A. Craxì, S. Petta, V. Calvaruso, M. Brunetto, B. Coco, L. Chessa, M.C. Pasetto, E. Bigliotti, F. Tamburrini, G. Montalto, A.R. Capitano, D. Ieluzzi, G. Fattovich, A.L. Zignego, M. Monti, L. Gragnani, M. Zuin, E. Finati, A. Giorgini, G. Angarano, M. Milella, F. Alessandro, M. Dallio, G. Mazzella, G. Lazzarini, M. Di Fine, F.P. Russo, A. Zanetto, F. Castelli, S. Zaltron, G. Raimondo, R. Filomia, M. Puoti, E. Danieli, M. Strazzabosco, M. Gemma, M. Angelico, F. De Leonardis, A. Gori, E. Cappelletti, R. Bruno, S. Cima, C. Coppola, D.C. Amoruso, P. Andreone, G. Simonetti, G.B. Gaeta, G. Brancaccio, P. Toniutto, D. Dissegna, M. Mondelli, S. Ludovisi, M. Persico, M. Masarone, C. Torti, A. Strazzulla, F. Rosina, L. Framarin, L.E. Weimer, M.G. Quaranta, L. Falzano, A. Mallano Aimilia Karampatou, Xue Han, Loreta A. Kondili, Gloria Taliani, Alessia Ciancio, Filomena Morisco, Rosina Maria Critelli, Enrica Baraldi, Veronica Bernabucci, Giulia Troshina, Maria Guarino, Simonetta Tagliavini, Federica D'Ambrosio, Laura Bristot, Laura Turco, Stefano Rosato, Stefano Vella, Tommaso Trenti, Isabella Neri, Antonio La Marca, Shivaji Manthena, Andrea S. Goldstein, Savino Bruno, Yanjun Bao, Yuri Sanchez Gonzalez, Erica Villa A. Craxì, S. Petta, V. Calvaruso, M. Brunetto, B. Coco, L. Chessa, M.C. Pasetto, E. Bigliotti, F. Tamburrini, G. Montalto, A.R. Capitano, D. Ieluzzi, G. Fattovich, A.L. Zignego, M. Monti, L. Gragnani, M. Zuin, E. Finati, A. Giorgini, G. Angarano, M. Milella, F. Alessandro, M. Dallio, G. Mazzella, G. Lazzarini, M. Di Fine, F.P. Russo, A. Zanetto, F. Castelli, S. Zaltron, G. Raimondo, R. Filomia, M. Puoti, E. Danieli, M. Strazzabosco, M. Gemma, M. Angelico, F. De Leonardis, A. Gori, E. Cappelletti, R. Bruno, S. Cima, C. Coppola, D.C. Amoruso, P. Andreone, G. Simonetti, G.B. Gaeta, G. Brancaccio, P. Toniutto, D. Dissegna, M. Mondelli, S. Ludovisi, M. Persico, M. Masarone, C. Torti, A. Strazzulla, F. Rosina, L. Framarin, L.E. Weimer, M.G. Quaranta, L. Falzano, A. Mallano Journal of Hepatology Volume 68, Issue 1, Pages 33-41 (January 2018) DOI: 10.1016/j.jhep.2017.08.019 Copyright © 2017 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2018 68, 33-41DOI: (10.1016/j.jhep.2017.08.019) Copyright © 2017 European Association for the Study of the Liver Terms and Conditions

Fig. 1 Levels of AMH in the serum of women who were HCV+, HBV+, or controls. (A) Mean serum levels (bars represent SD and bold lines inside the box plot median levels). Levels of significance: *p = 0.011; ^p = 0.009 (Mann–Whitney U-test). (B) Distributions of normal and menopausal serum levels of AMH among women in the HCV+, HBV+, and control groups. A significant difference was present between women who were HCV+ vs. those who were HBV+ (°) or controls (°°). Levels of significance: °,°°: p <0.0001 (Chi-square test). AMH, anti-Müllerian hormone. Journal of Hepatology 2018 68, 33-41DOI: (10.1016/j.jhep.2017.08.019) Copyright © 2017 European Association for the Study of the Liver Terms and Conditions

Fig. 2 Relationship between IGF-1 and AMH levels in the serum of women who were HCV+ or HBV+. Different panels report the correlation between IGF-1 and (A) AMH, (B) liver stiffness, (C) grade of inflammation, and (D) stage. Lines represent the best-fit regression line for each subgroup. Data were analysed by Pearson correlation test. AMH, anti-Müllerian hormone; IGF, insulin-like growth factor. Journal of Hepatology 2018 68, 33-41DOI: (10.1016/j.jhep.2017.08.019) Copyright © 2017 European Association for the Study of the Liver Terms and Conditions