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EVEROLIMUS ASSOCIATO A DOSI MOLTO BASSE DI CYA DETERMINA ELEVATO GFR RISPETTO AL TRATTAMENTO STANDARD AIDA LARTI E. Bertoni, G. Rosso, L. Di Maria, M. Zanazzi and M. Salvadori Renal Unit Careggi University Hospital – Florence ,Italy
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AIM OF THE STUDY PATIENTS AND METHODS
Aim of the study was to compare in cadaveric renal transplant recipients the efficacy of CyA “very low dose” with Everolimus “high dose” with respect to CyA “standard dose” with EC-MPS PATIENTS AND METHODS In a randomized, prospective, monocenter, open study, 106 patients were enrolled to receive : 56 pts : Everolimus (to reach C ng/ml) + CyA (to reach C ng/ml ) + steroids 50 pts : EC-MPS (1440 mg/day) + Cya (to reach C ng/ml) + steroids - Efficacy was evaluated at 3 and 12 months - Data analyses have been made per protocol Efficacy was evaluated at 3 and 12 months. Data analyses have been made per protocol
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RESULTS I
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RESULTS II
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RESULTS
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