Conosci la citologia ? Livello 1 Avrai 60 secondi per rispondere ad ogni immagine. Puoi rispondere cliccando Reactive change oppure More than reactive.

Conosci la citologia ? Livello 1 Avrai 60 secondi per rispondere ad ogni immagine. Puoi rispondere cliccando Reactive change oppure More than reactive change oppure Normal

Reactive ChangeMore than Reactive Change 1 Normal

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Reactive Change More than Reactive Change 29 Normal

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Image 1: reactive changes Smear with marked inflammation: many granulocytes and histiocytes. (obj. 20x) Image 2: reactive changes Menopausal atrophy with large sheets of parabasal or basal cells and some naked nuclei. (obj. 20x) Image 3 – reactive changes Metaplasia: enlarged nuclei with regular chromatin and abundant cytoplasm. This change is not typical of ASC-US. Repair change. (obj. 40x) Image 4 – reactive changes Exocervical smear with aggregates of anucleate squames (hyperkeratosis) and sheets of parakeratotic cells. (obj. 10x) Image 5 – changes more than reactive, to send for a second opinion ASCUS: inflammatory ectocervix with some intermediate squamous cells with enlarged nuclei and narrow perinuclear halos. (obj. 20x) Image 6 – reactive changes metaplastic cells with enlarged nuclei. This change is not typical of ASC-US. (obj. 20x) Image 7 – changes more than reactive, to send for a second opinion L-SIL: eosinophilic squamous cells with a perinuclear empty cavity surrounded by cytoplasmic thickening and with moderate nuclear enlargement: typical koilocytes. (obj. 20x) Image 8 – changes more than reactive, to send for a second opinion L-SIL: eosinophilic squamous cells with dense cytoplasm, parakeratosis and some typical koilocytes. (obj. 20x). ricomincia

Image 9 – reactive changes Squamous metaplasia: sheet of metaplastic squamous cells. (obj. 20x) Image 10 - normal Intermediate and superficial squamous cells, basophilic or eosinophilic. Some polymorphs are present. (obj. 10x) Image 11 – reactive changes Parakeratosis. (obj. 20x) Image 12 – reactive changes A large, multinucleated histiocyte (obj. 40x) Image 13 - normal A sheet of normal secretory glandular cells with a typical honeycomb pattern. (obj. 40x) Image 14 – reactive changes metaplastic cells with enlarged nuclei. This change is not typical of ASC-US. (obj. 20x) Image 15 - normal Basophilic squamous cells with macrophages and granulocytes. (obj. 20x) Image 16 – reactive changes Repair cells with clear chromatin and nucleoli, probably superimposed to squamous metaplasia: look also some nuclear grooves. (obj. 40x). Remember that repair are sheets of cells with abundant cytoplasm, enlarged nuclei (but N/C ratio near normal), with a granular chromatin and a prominent nucleoli, in a more or less inflammatory background. ricomincia

Image 17 – changes more than reactive, to send for a second opinion ASCUS: squamous cell with a nucleus more than twice the normal diameter and irregular (obj. 40x) Image 18 – reactive changes Squamous metaplasia: sheet of metaplastic squamous cells. Image 19 – changes more than reactive, to send for a second opinion ASCUS: eosinophilic squamous cell with enlarged and hyperchromatic nucleus. (obj. 20x) Image 20 - normal Sheet of glandular endocervical cells seen at medium magnification. Compare nuclear sizes of columnar cells and the intermediate squamous cell. (obj. 20x) Image 21 – reactive changes Herpetic infection: multinucleated cells with smudgy nuclei looking like ground glass. (obj. 20x) Image 22 – changes more than reactive, to send for a second opinion L-SIL: squamous cells with an enlarged nucleus, surrounded by an ill-defined clear halo, associated with parakeratotic cells. (obj. 20x) Image 23 – reactive changes Mycosis: hyphae and yeasts of Candida albicans in an inflammatory background. (obj. 20x) Image 24 – changes more than reactive, to send for a second opinion L-SIL: squamous cells with an enlarged nucleus, surrounded by an ill-defined clear halo, associated with parakeratotic cells: (obj. 20x) ricomincia

Image 25 - normal Endometrial cells in under 40 year-old woman, not menopaused. (obj. 20x) Image 26 – reactive changes Squamous cells with reactive changes with a clear perinuclear halo and a nucleus increased in size: look for trichomonas or fungi (obj.10x) Image 27 – changes more than reactive, to send for a second opinion ASCUS: eosinophilic squamous cell with an enlarged nucleus but with pale chromatin. (obj. 20x) Image 28 – changes more than reactive, to send for a second opinion L-SIL: basophilic koilocytes and normal intermediate and superficial squamous cells. (obj. 40x) Image 29 – reactive changes Inflammatory smear with intermediate and superficial squamous cells having enlarged nuclei: look for Trichomonas or Gardnerella. Image 30 – reactive changes Bacteria are seen in the background, mainly on the squamous cells resulting in clue cells. Granulocytes are absent or rare. (obj. 20x) ricomincia

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Conosci la citologia ? Livello 1 Avrai 60 secondi per rispondere ad ogni immagine. Puoi rispondere cliccando Reactive change oppure More than reactive.

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