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Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation by Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, Adelmo.

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Presentazione sul tema: "Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation by Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, Adelmo."— Transcript della presentazione:

1 Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation by Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Flora Castellino, Elisabetta Bonifacio, Beatrice Del Papa, Tiziana Zei, Roberta Iacucci Ostini, Debora Cecchini, Teresa Aloisi, Katia Perruccio, Loredana Ruggeri, Chiara Balucani, Antonio Pierini, Paolo Sportoletti, Cynthia Aristei, Brunangelo Falini, Yair Reisner, Andrea Velardi, Franco Aversa, and Massimo F. Martelli Blood Volume 117(14): April 7, 2011 ©2011 by American Society of Hematology

2 Overall view of the protocol. Mauro Di Ianni et al. Blood 2011;117: ©2011 by American Society of Hematology

3 Immunophenotype of the immunoselected Tregs. Mauro Di Ianni et al. Blood 2011;117: ©2011 by American Society of Hematology

4 Immunophenotype of the immunoselected Tregs. Mauro Di Ianni et al. Blood 2011;117: ©2011 by American Society of Hematology

5 Immunologic reconstitution after Treg-based transplantation. Mauro Di Ianni et al. Blood 2011;117: ©2011 by American Society of Hematology

6 Immunologic reconstitution after Treg-based transplantation. Mauro Di Ianni et al. Blood 2011;117: ©2011 by American Society of Hematology

7 Regeneration of alloreactive NK-cell repertoires against a KIR-ligand–mismatched target. Mauro Di Ianni et al. Blood 2011;117: ©2011 by American Society of Hematology


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