Low Levels of Genetic Heterogeneity in Matched Lymph Node Metastases from Patients with Melanoma  Milena Casula, Maria Colombino, Antonella Manca, Corrado.

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Low Levels of Genetic Heterogeneity in Matched Lymph Node Metastases from Patients with Melanoma  Milena Casula, Maria Colombino, Antonella Manca, Corrado Caracò, Gerardo Botti, Paolo A. Ascierto, Amelia Lissia, Antonio Cossu, Giuseppe Palmieri Nicola Mozzillo, Panagiotis Paliogiannis, Paola Queirolo, Corrado Rubino, MariaCristina Sini, Ignazio Stanganelli, Francesco Tanda Milena Casula, Maria Colombino, Antonella Manca, Corrado Caracò, Gerardo Botti, Paolo A. Ascierto, Amelia Lissia, Antonio Cossu, Giuseppe Palmieri Nicola Mozzillo, Panagiotis Paliogiannis, Paola Queirolo, Corrado Rubino, MariaCristina Sini, Ignazio Stanganelli, Francesco Tanda  Journal of Investigative Dermatology  Volume 136, Issue 9, Pages 1917-1920 (September 2016) DOI: 10.1016/j.jid.2016.05.103 Copyright © 2016 The Authors Terms and Conditions

Figure 1 Distribution of nonsilent sequence variations in melanoma samples. Individual gene mutations (blue squares) and polymorphic sequence variants with unknown functional significance (red squares) are shown across all cases. Sample results for the four discrepant cases are indicated with darker colors into the right part of the diagram. La and Lb, the two paired lymph node samples from each patient; P, primary melanoma. Journal of Investigative Dermatology 2016 136, 1917-1920DOI: (10.1016/j.jid.2016.05.103) Copyright © 2016 The Authors Terms and Conditions