Carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma: a multicenter, phase 2 study by Sara Bringhen, Maria.

Slides:



Advertisements
Presentazioni simili
Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia by Andrea Pession, Riccardo Masetti,
Advertisements

Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the.
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation by Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, Adelmo.
Carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma: a multicenter, phase 2 study by Sara Bringhen, Maria.
Efficacy and safety of once-weekly bortezomib in multiple myeloma patients by Sara Bringhen, Alessandra Larocca, Davide Rossi, Maide Cavalli, Mariella.
Additional chromosomal abnormalities in Philadelphia- positive clone: adverse prognostic influence on frontline imatinib therapy: a GIMEMA Working Party.
Deferiprone Versus Deferoxamine in Thalassemia Intermedia: Results from 5-Year Long-Term Italian Multi- Center Randomized Clinical Trial by Angela Vitrano,
PET/CT Is a Useful Tool For Both Refining The Definition Of Complete Response (CR) In Multiple Myeloma (MM) and Detecting Otherwise Unrevealed Progression.
Randomized Trial of Busulfan with Cyclophosphamide Versus Busulfan with Fludarabine As Preparative Regimen to Allogeneic Hematopoietic Stem Cell Transplantation.
Long-Term Outcome to First-Line Imatinib according to 2013 European LeukemiaNet Response Criteria: a GIMEMA CML WP Analysis by Fausto Castagnetti, Gabriele.
UP-TO-DATE SULL’ISCHEMIA CRITICA Influenza dei fattori di rischio Andrea Semplicini Medicina Interna 1 - Ospedale di Venezia Azienda ULSS 12 Veneziana.
Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia by Luca Malcovati, Elli Papaemmanuil, Ilaria Ambaglio,
Lucia Del Mastro Gruppo Italiano Mammella - GIM Napoli 10 marzo 2017
Venoarterial Extracorporeal Membrane Oxygenation for Acute Fulminant Myocarditis in Adult Patients: A 5-Year Multi-Institutional Experience  Roberto Lorusso,
American Heart Journal
Transcatheter Aortic Valve Implantation in Patients With Advanced Chronic Kidney Disease  Federico Conrotto, MD, Stefano Salizzoni, MD, Alessandro Andreis,
Cetuximab plus irinotecan after irinotecan failure in elderly metastatic colorectal cancer patients: Clinical outcome according to KRAS and BRAF mutational.
Acute diplopia in the pediatric Emergency Department
Current challenges in HER2-positive breast cancer
Volume 56, Issue 6, Pages (December 1999)
Volume 126, Issue 5, Pages (November 2004)
Heart failure and anemia: Effects on prognostic variables
Assessing the role of eptifibatide in patients with diffuse coronary disease undergoing drug-eluting stenting: The INtegrilin plus STenting to Avoid myocardial.
S. Rizza, M. Copetti, C. Rossi, M. A. Cianfarani, M. Zucchelli, A
A Cytologic Assay for Diagnosis of Food Hypersensitivity in Patients With Irritable Bowel Syndrome  Antonio Carroccio, Ignazio Brusca, Pasquale Mansueto,
Volume 126, Issue 1, Pages (January 2004)
Critical Reviews in Oncology / Hematology
Volume 132, Issue 7, Pages (June 2007)
An open-label, pilot study of fludarabine, cyclophosphamide, and alemtuzumab in relapsed/refractory patients with B-cell chronic lymphocytic leukemia by.
Volume 119, Issue 1, Pages (July 2000)
Persistent Improvement In Clinical Outcomes With Bortezomib-Thalidomide-Dexamethasone Vs Thalidomide-Dexamethasone Incorporated Into Double Autologous.
MP84-13 A NEW APPROACH FOR AN IMPROVED PSA DOUBLING TIME COMPUTATION FOR SELECTING PATIENTS CANDIDATE TO TIMELY SALVAGE RADIOTHERAPY FOR A BIOCHEMICAL.
Utility of baseline 18FDG-PET/CT functional parameters in defining prognosis of primary mediastinal (thymic) large B-cell lymphoma by Luca Ceriani, Maurizio.
Bendamustine, Low-Dose Dexamethasone, and Lenalidomide (BdL) For The Treatment Of Patients With Relapsed Multiple Myeloma Confirms Very Promising Results.
Positive Selection and Transplantation of Autologous Highly Purified CD133+ Stem Cells in Resistant/Relapsed Chronic Lymphocytic Leukemia Patients Results.
A Predictive Model Identifies Patients Most Likely to Have Inadequate Bowel Preparation for Colonoscopy  Cesare Hassan, Lorenzo Fuccio, Mario Bruno, Nico.
Volume 56, Issue 6, Pages (December 1999)
Impact of New Drugs on the Long-Term Follow-Up of Upfront Tandem Autograft– Allograft in Multiple Myeloma  Luisa Giaccone, Andrea Evangelista, Francesca.
Allogeneic Hematopoietic Cell Transplantation from Unrelated Donors in Multiple Myeloma: Study from the Italian Bone Marrow Donor Registry  Roberto Passera,
The Long-Term Outcome Of Adult Patients With Acute Myeloid Leukemia NPM+ and FLT3/ITD- Is Not Significantly Improved By The Application Of An Allogeneic.
NF1 Gene Mutations Represent the Major Molecular Event Underlying Neurofibromatosis-Noonan Syndrome  Alessandro De Luca, Irene Bottillo, Anna Sarkozy,
Posterior Reversible Encephalopathy Syndrome after Hematopoietic Cell Transplantation in Children with Hemoglobinopathies  Javid Gaziev, Simone Marziali,
Use of office hysteroscopy to empty a very large hematometra in a young virgin patient with mosaic Turner’s syndrome  Attilio Di Spiezio Sardo, M.D.,
Post-Transplant Cyclophosphamide and Tacrolimus–Mycophenolate Mofetil Combination Prevents Graft-versus-Host Disease in Allogeneic Peripheral Blood Hematopoietic.
Multicenter Experience Using Total Lymphoid Irradiation and Antithymocyte Globulin as Conditioning for Allografting in Hematological Malignancies  Giuseppe.
A Cytologic Assay for Diagnosis of Food Hypersensitivity in Patients With Irritable Bowel Syndrome  Antonio Carroccio, Ignazio Brusca, Pasquale Mansueto,
Volume 51, Issue 4, Pages (April 2007)
Diagnostic Performance of Low-Dose Computed Tomography Screening for Lung Cancer over Five Years  Giulia Veronesi, MD, Patrick Maisonneuve, DipEng, Lorenzo.
Activation of immune responses in patients with relapsed-metastatic head and neck cancer (CONFRONT phase I-II trial): Multimodality immunotherapy with.
Trattamento lesioni sopra e sotto il ginocchio:
Volume 124, Issue 5, Pages (May 2003)
A randomized study on eversion versus standard carotid endarterectomy: Study design and preliminary results: The Everest Trial  Piergiorgio Cao, MD, Giuseppe.
Preliminary results of endovascular aneurysm sealing from the multicenter Italian Research on Nellix Endoprosthesis (IRENE) study  Bruno Gossetti, MD,
Incidence and Outcome of Invasive Fungal Diseases after Allogeneic Stem Cell Transplantation: A Prospective Study of the Gruppo Italiano Trapianto Midollo.
Andrea Morciano, M. D. , Federica Romani, M. D
P Role of microRNAs as Biomarkers of Malignant Mesothelioma in Patients with Pleural Effusion  Alessandro Palleschi, Valentina Bollati, Chiara.
Triazole resistance in Aspergillus fumigatus isolates from patients with cystic fibrosis in Italy  Anna Prigitano, Maria Carmela Esposto, Arianna Biffi,
Handgrip Strength Predicts Persistent Walking Recovery After Hip Fracture Surgery  Elisabetta Savino, MD, Emilio Martini, MD, Fulvio Lauretani, MD, Giulio.
Volume 56, Issue 6, Pages (December 1999)
Discoid or segmental rectosigmoid resection for deep infiltrating endometriosis: a case- control study  Francesco Fanfani, M.D., Anna Fagotti, M.D., Maria.
Post-Transplant Cyclophosphamide and Tacrolimus–Mycophenolate Mofetil Combination Prevents Graft-versus-Host Disease in Allogeneic Peripheral Blood Hematopoietic.
Predictors of outcome in ICU patients with septic shock caused by Klebsiella pneumoniae carbapenemase–producing K. pneumoniae  M. Falcone, A. Russo, A.
Is there a role for soy isoflavones in the therapeutic approach to polycystic ovary syndrome? Results from a pilot study  Daniela Romualdi, M.D., Barbara.
MITO 31 A phase II trial of Olaparib in patients with recurrent ovarian cancer wild type for germline and somatic BRCA mutations: a MITO translational.
High-Dose Melphalan Plus Thiotepa as Conditioning Regimen before Second Autologous Stem Cell Transplantation for “De Novo” Multiple Myeloma Patients:
A 10-day levofloxacin-based therapy in patients with resistant Helicobacter pylori infection: A controlled trial  Claudio Bilardi, Pietro Dulbecco, Patrizia.
Gastrointestinal Endoscopy
Outcomes of Children with Hemophagocytic Lymphohistiocytosis Given Allogeneic Hematopoietic Stem Cell Transplantation in Italy  Chiara Messina, Marco.
Age-sex–specific ranges of platelet count and all-cause mortality: prospective findings from the MOLI-SANI study by Marialaura Bonaccio, Augusto Di Castelnuovo,
Recommendations for the Analysis of ALK Gene Rearrangements in Non–Small-Cell Lung Cancer: A Consensus of the Italian Association of Medical Oncology.
Transcript della presentazione:

Carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma: a multicenter, phase 2 study by Sara Bringhen, Maria Teresa Petrucci, Alessandra Larocca, Concetta Conticello, Davide Rossi, Valeria Magarotto, Pellegrino Musto, Luana Boccadifuoco, Massimo Offidani, Paola Omedé, Fabiana Gentilini, Giovannino Ciccone, Giulia Benevolo, Mariella Genuardi, Vittorio Montefusco, Stefania Oliva, Tommaso Caravita, Paola Tacchetti, Mario Boccadoro, Pieter Sonneveld, and Antonio Palumbo Blood Volume 124(1):63-69 July 3, 2014 ©2014 by American Society of Hematology

Kaplan-Meier analysis of time to response, showing proportion of responding patients achieving their best response over time. Kaplan-Meier analysis of time to response, showing proportion of responding patients achieving their best response over time. Sara Bringhen et al. Blood 2014;124:63-69 ©2014 by American Society of Hematology

Kaplan-Meier analysis of time to events data. Kaplan-Meier analysis of time to events data. (A) PFS. (B) OS. Sara Bringhen et al. Blood 2014;124:63-69 ©2014 by American Society of Hematology